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resource source identifier cyclin d1 recombinant rabbit monoclonal antibody (sp4) thermo fisher ca#ma5-16356  (Thermo Fisher)


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    Thermo Fisher resource source identifier cyclin d1 recombinant rabbit monoclonal antibody (sp4) thermo fisher ca#ma5-16356
    Resource Source Identifier Cyclin D1 Recombinant Rabbit Monoclonal Antibody (Sp4) Thermo Fisher Ca#Ma5 16356, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/cyclin+d1+sp4+antibody/Collagen/pm38091982-140-2-13
    Average 99 stars, based on 1 article reviews
    resource source identifier cyclin d1 recombinant rabbit monoclonal antibody (sp4) thermo fisher ca#ma5-16356 - by Bioz Stars, 2026-09
    99/100 stars

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    Related Articles

    Blocking Assay:

    Article Title: A Genetic Progression Model of Braf V600E -Induced Intestinal Tumorigenesis Reveals Targets for Therapeutic Intervention
    Article Snippet: For immunohistochemistry formalin-fixed paraffin-embedded tissue sections were dewaxed and placed in a microwave (10 min., 600 watt) to recover antigens before incubation with the following primary antibodies: p53 (NCL-p53-CM5p, Leica Micosystems, Wetzlar, Germany), p21 (C-19) (sc-397; Santa Cruz Biotechnology, Heidelberg, Germany), -catenin (#610154, BD Biosciences, San Diego, CA), phospho- p44/42 MAPK (Erk1/2 Thr202/Tyr204) (D13.14.4E XP, Cell Signaling), Ki-67 (SP6, DCS Hamburg, Germany), c-Myc (N-262) (sc-764, Santa Cruz), cyclin D1 (SP4, Thermo Scientific, Waltham, MA) and cytokeratin 20 (GP-K20, Progen, Heidelberg, Germany).

    Article Title: Plasmacytic ALK-positive large B-cell lymphoma: a potential mimic of extramedullary plasmacytoma.
    Article Snippet: To the Editor: ALK-positive large B-cell lymphoma (ALK+ LBCL) is defined as a B-cell neoplasm that expresses the ALK protein.. This lymphoma occurs in all age groups with a male predominance (M:F ratio, 3:1).. Although the tumor mainly involves lymph nodes, the involvement of various extranodal sites including the gastrointestinal (GI) tract, ovaries, nasopharynx, tongue, brain, liver, bone and spleen has been reported.

    Article Title: Novel Karyotypes and Cyclin D1 Immunoreactivity in Clear Cell Sarcoma of the Kidney
    Article Snippet: Pathological diagnosis of clear cell sarcoma of the kidney (CCSK) is challenging as it resembles blastemal Wilms tumor (WT) and other pediatric sarcomas, and does not have any distinctive immunophenotype.. The YWHAEFAM22 translocation t(10;17)(q22;p13) has been reported in a subset of CCSK.. This translocation also occurs in high-grade endometrial sarcoma, in which it is associated with cyclin D1 overexpression.

    Article Title: Characterization of molecular signatures of supratentorial ependymomas.
    Article Snippet: The primary antibodies used were cyclin D1 (1:250 dilution, clone SP4, Thermo Fisher Scientific, Waltham, MA), p65 (1:5000 dilution, clone D14E12, Cell Signaling, Danvers, MA), and L1CAM (1:2000 dilution, clone UJ127.11, Sigma, St. Louis, MO).

    Article Title: Significance of COX-2 and VEGF expression in histopathologic grading and invasiveness of meningiomas.
    Article Snippet: Meningiomas are slow-growing neoplasms that recur locally.. Their morphologic grading does not always correlate with patient outcome.. We evaluated the status of several immunohistochemical markers with histopathologic parameters in various grades of meningioma.Eighty-eight meningioma specimens were examined immunohistochemically to determine the status of Ki-67, cyclin D1, epidermal growth factor receptor (EGFR), cyclooxygenase-2 (COX-2), vascular endothelial growth factor (VEGF), and bcl-2.

    Article Title: CK1α ablation in keratinocytes induces p53-dependent, sunburn-protective skin hyperpigmentation
    Article Snippet: After blocking, sections were incubated overnight at 4 °C with antibodies to the following markers at a proper dilution: CK1α (C-19, 1/1,000; Santa Cruz), γ-H2AX (JBW301, 1/3,000; Millipore), p53 (CM5, 1/200; Leica Biosystems), p21 (F-5, 1/100; Santa Cruz), β-catenin (14 β-catenin, 1/100; BD Bioscience), cyclin D1 (SP4, 1/200; Thermo Fisher Scientific), cleaved caspase 3 (Asp175, 1/200; Cell Signaling Technology), and TRP1 (ab3312, 1/200; Abcam).

    Incubation:

    Article Title: A Genetic Progression Model of Braf V600E -Induced Intestinal Tumorigenesis Reveals Targets for Therapeutic Intervention
    Article Snippet: For immunohistochemistry formalin-fixed paraffin-embedded tissue sections were dewaxed and placed in a microwave (10 min., 600 watt) to recover antigens before incubation with the following primary antibodies: p53 (NCL-p53-CM5p, Leica Micosystems, Wetzlar, Germany), p21 (C-19) (sc-397; Santa Cruz Biotechnology, Heidelberg, Germany), -catenin (#610154, BD Biosciences, San Diego, CA), phospho- p44/42 MAPK (Erk1/2 Thr202/Tyr204) (D13.14.4E XP, Cell Signaling), Ki-67 (SP6, DCS Hamburg, Germany), c-Myc (N-262) (sc-764, Santa Cruz), cyclin D1 (SP4, Thermo Scientific, Waltham, MA) and cytokeratin 20 (GP-K20, Progen, Heidelberg, Germany).

    Article Title: Plasmacytic ALK-positive large B-cell lymphoma: a potential mimic of extramedullary plasmacytoma.
    Article Snippet: To the Editor: ALK-positive large B-cell lymphoma (ALK+ LBCL) is defined as a B-cell neoplasm that expresses the ALK protein.. This lymphoma occurs in all age groups with a male predominance (M:F ratio, 3:1).. Although the tumor mainly involves lymph nodes, the involvement of various extranodal sites including the gastrointestinal (GI) tract, ovaries, nasopharynx, tongue, brain, liver, bone and spleen has been reported.

    Article Title: Novel Karyotypes and Cyclin D1 Immunoreactivity in Clear Cell Sarcoma of the Kidney
    Article Snippet: Pathological diagnosis of clear cell sarcoma of the kidney (CCSK) is challenging as it resembles blastemal Wilms tumor (WT) and other pediatric sarcomas, and does not have any distinctive immunophenotype.. The YWHAEFAM22 translocation t(10;17)(q22;p13) has been reported in a subset of CCSK.. This translocation also occurs in high-grade endometrial sarcoma, in which it is associated with cyclin D1 overexpression.

    Article Title: Characterization of molecular signatures of supratentorial ependymomas.
    Article Snippet: The primary antibodies used were cyclin D1 (1:250 dilution, clone SP4, Thermo Fisher Scientific, Waltham, MA), p65 (1:5000 dilution, clone D14E12, Cell Signaling, Danvers, MA), and L1CAM (1:2000 dilution, clone UJ127.11, Sigma, St. Louis, MO).

    Article Title: Significance of COX-2 and VEGF expression in histopathologic grading and invasiveness of meningiomas.
    Article Snippet: Meningiomas are slow-growing neoplasms that recur locally.. Their morphologic grading does not always correlate with patient outcome.. We evaluated the status of several immunohistochemical markers with histopathologic parameters in various grades of meningioma.Eighty-eight meningioma specimens were examined immunohistochemically to determine the status of Ki-67, cyclin D1, epidermal growth factor receptor (EGFR), cyclooxygenase-2 (COX-2), vascular endothelial growth factor (VEGF), and bcl-2.

    Article Title: CK1α ablation in keratinocytes induces p53-dependent, sunburn-protective skin hyperpigmentation
    Article Snippet: After blocking, sections were incubated overnight at 4 °C with antibodies to the following markers at a proper dilution: CK1α (C-19, 1/1,000; Santa Cruz), γ-H2AX (JBW301, 1/3,000; Millipore), p53 (CM5, 1/200; Leica Biosystems), p21 (F-5, 1/100; Santa Cruz), β-catenin (14 β-catenin, 1/100; BD Bioscience), cyclin D1 (SP4, 1/200; Thermo Fisher Scientific), cleaved caspase 3 (Asp175, 1/200; Cell Signaling Technology), and TRP1 (ab3312, 1/200; Abcam).

    Activation Assay:

    Article Title: A Genetic Progression Model of Braf V600E -Induced Intestinal Tumorigenesis Reveals Targets for Therapeutic Intervention
    Article Snippet: For immunohistochemistry formalin-fixed paraffin-embedded tissue sections were dewaxed and placed in a microwave (10 min., 600 watt) to recover antigens before incubation with the following primary antibodies: p53 (NCL-p53-CM5p, Leica Micosystems, Wetzlar, Germany), p21 (C-19) (sc-397; Santa Cruz Biotechnology, Heidelberg, Germany), -catenin (#610154, BD Biosciences, San Diego, CA), phospho- p44/42 MAPK (Erk1/2 Thr202/Tyr204) (D13.14.4E XP, Cell Signaling), Ki-67 (SP6, DCS Hamburg, Germany), c-Myc (N-262) (sc-764, Santa Cruz), cyclin D1 (SP4, Thermo Scientific, Waltham, MA) and cytokeratin 20 (GP-K20, Progen, Heidelberg, Germany).

    Article Title: Plasmacytic ALK-positive large B-cell lymphoma: a potential mimic of extramedullary plasmacytoma.
    Article Snippet: To the Editor: ALK-positive large B-cell lymphoma (ALK+ LBCL) is defined as a B-cell neoplasm that expresses the ALK protein.. This lymphoma occurs in all age groups with a male predominance (M:F ratio, 3:1).. Although the tumor mainly involves lymph nodes, the involvement of various extranodal sites including the gastrointestinal (GI) tract, ovaries, nasopharynx, tongue, brain, liver, bone and spleen has been reported.

    Article Title: Novel Karyotypes and Cyclin D1 Immunoreactivity in Clear Cell Sarcoma of the Kidney
    Article Snippet: Pathological diagnosis of clear cell sarcoma of the kidney (CCSK) is challenging as it resembles blastemal Wilms tumor (WT) and other pediatric sarcomas, and does not have any distinctive immunophenotype.. The YWHAEFAM22 translocation t(10;17)(q22;p13) has been reported in a subset of CCSK.. This translocation also occurs in high-grade endometrial sarcoma, in which it is associated with cyclin D1 overexpression.

    Article Title: Characterization of molecular signatures of supratentorial ependymomas.
    Article Snippet: The primary antibodies used were cyclin D1 (1:250 dilution, clone SP4, Thermo Fisher Scientific, Waltham, MA), p65 (1:5000 dilution, clone D14E12, Cell Signaling, Danvers, MA), and L1CAM (1:2000 dilution, clone UJ127.11, Sigma, St. Louis, MO).

    Article Title: Significance of COX-2 and VEGF expression in histopathologic grading and invasiveness of meningiomas.
    Article Snippet: Meningiomas are slow-growing neoplasms that recur locally.. Their morphologic grading does not always correlate with patient outcome.. We evaluated the status of several immunohistochemical markers with histopathologic parameters in various grades of meningioma.Eighty-eight meningioma specimens were examined immunohistochemically to determine the status of Ki-67, cyclin D1, epidermal growth factor receptor (EGFR), cyclooxygenase-2 (COX-2), vascular endothelial growth factor (VEGF), and bcl-2.

    Article Title: CK1α ablation in keratinocytes induces p53-dependent, sunburn-protective skin hyperpigmentation
    Article Snippet: After blocking, sections were incubated overnight at 4 °C with antibodies to the following markers at a proper dilution: CK1α (C-19, 1/1,000; Santa Cruz), γ-H2AX (JBW301, 1/3,000; Millipore), p53 (CM5, 1/200; Leica Biosystems), p21 (F-5, 1/100; Santa Cruz), β-catenin (14 β-catenin, 1/100; BD Bioscience), cyclin D1 (SP4, 1/200; Thermo Fisher Scientific), cleaved caspase 3 (Asp175, 1/200; Cell Signaling Technology), and TRP1 (ab3312, 1/200; Abcam).

    Protein-Protein interactions:

    Article Title: A Genetic Progression Model of Braf V600E -Induced Intestinal Tumorigenesis Reveals Targets for Therapeutic Intervention
    Article Snippet: For immunohistochemistry formalin-fixed paraffin-embedded tissue sections were dewaxed and placed in a microwave (10 min., 600 watt) to recover antigens before incubation with the following primary antibodies: p53 (NCL-p53-CM5p, Leica Micosystems, Wetzlar, Germany), p21 (C-19) (sc-397; Santa Cruz Biotechnology, Heidelberg, Germany), -catenin (#610154, BD Biosciences, San Diego, CA), phospho- p44/42 MAPK (Erk1/2 Thr202/Tyr204) (D13.14.4E XP, Cell Signaling), Ki-67 (SP6, DCS Hamburg, Germany), c-Myc (N-262) (sc-764, Santa Cruz), cyclin D1 (SP4, Thermo Scientific, Waltham, MA) and cytokeratin 20 (GP-K20, Progen, Heidelberg, Germany).

    Article Title: Plasmacytic ALK-positive large B-cell lymphoma: a potential mimic of extramedullary plasmacytoma.
    Article Snippet: To the Editor: ALK-positive large B-cell lymphoma (ALK+ LBCL) is defined as a B-cell neoplasm that expresses the ALK protein.. This lymphoma occurs in all age groups with a male predominance (M:F ratio, 3:1).. Although the tumor mainly involves lymph nodes, the involvement of various extranodal sites including the gastrointestinal (GI) tract, ovaries, nasopharynx, tongue, brain, liver, bone and spleen has been reported.

    Article Title: Novel Karyotypes and Cyclin D1 Immunoreactivity in Clear Cell Sarcoma of the Kidney
    Article Snippet: Pathological diagnosis of clear cell sarcoma of the kidney (CCSK) is challenging as it resembles blastemal Wilms tumor (WT) and other pediatric sarcomas, and does not have any distinctive immunophenotype.. The YWHAEFAM22 translocation t(10;17)(q22;p13) has been reported in a subset of CCSK.. This translocation also occurs in high-grade endometrial sarcoma, in which it is associated with cyclin D1 overexpression.

    Article Title: Characterization of molecular signatures of supratentorial ependymomas.
    Article Snippet: The primary antibodies used were cyclin D1 (1:250 dilution, clone SP4, Thermo Fisher Scientific, Waltham, MA), p65 (1:5000 dilution, clone D14E12, Cell Signaling, Danvers, MA), and L1CAM (1:2000 dilution, clone UJ127.11, Sigma, St. Louis, MO).

    Article Title: Significance of COX-2 and VEGF expression in histopathologic grading and invasiveness of meningiomas.
    Article Snippet: Meningiomas are slow-growing neoplasms that recur locally.. Their morphologic grading does not always correlate with patient outcome.. We evaluated the status of several immunohistochemical markers with histopathologic parameters in various grades of meningioma.Eighty-eight meningioma specimens were examined immunohistochemically to determine the status of Ki-67, cyclin D1, epidermal growth factor receptor (EGFR), cyclooxygenase-2 (COX-2), vascular endothelial growth factor (VEGF), and bcl-2.

    Article Title: CK1α ablation in keratinocytes induces p53-dependent, sunburn-protective skin hyperpigmentation
    Article Snippet: After blocking, sections were incubated overnight at 4 °C with antibodies to the following markers at a proper dilution: CK1α (C-19, 1/1,000; Santa Cruz), γ-H2AX (JBW301, 1/3,000; Millipore), p53 (CM5, 1/200; Leica Biosystems), p21 (F-5, 1/100; Santa Cruz), β-catenin (14 β-catenin, 1/100; BD Bioscience), cyclin D1 (SP4, 1/200; Thermo Fisher Scientific), cleaved caspase 3 (Asp175, 1/200; Cell Signaling Technology), and TRP1 (ab3312, 1/200; Abcam).

    Injection:

    Article Title: A Genetic Progression Model of Braf V600E -Induced Intestinal Tumorigenesis Reveals Targets for Therapeutic Intervention
    Article Snippet: For immunohistochemistry formalin-fixed paraffin-embedded tissue sections were dewaxed and placed in a microwave (10 min., 600 watt) to recover antigens before incubation with the following primary antibodies: p53 (NCL-p53-CM5p, Leica Micosystems, Wetzlar, Germany), p21 (C-19) (sc-397; Santa Cruz Biotechnology, Heidelberg, Germany), -catenin (#610154, BD Biosciences, San Diego, CA), phospho- p44/42 MAPK (Erk1/2 Thr202/Tyr204) (D13.14.4E XP, Cell Signaling), Ki-67 (SP6, DCS Hamburg, Germany), c-Myc (N-262) (sc-764, Santa Cruz), cyclin D1 (SP4, Thermo Scientific, Waltham, MA) and cytokeratin 20 (GP-K20, Progen, Heidelberg, Germany).

    Article Title: Plasmacytic ALK-positive large B-cell lymphoma: a potential mimic of extramedullary plasmacytoma.
    Article Snippet: To the Editor: ALK-positive large B-cell lymphoma (ALK+ LBCL) is defined as a B-cell neoplasm that expresses the ALK protein.. This lymphoma occurs in all age groups with a male predominance (M:F ratio, 3:1).. Although the tumor mainly involves lymph nodes, the involvement of various extranodal sites including the gastrointestinal (GI) tract, ovaries, nasopharynx, tongue, brain, liver, bone and spleen has been reported.

    Article Title: Novel Karyotypes and Cyclin D1 Immunoreactivity in Clear Cell Sarcoma of the Kidney
    Article Snippet: Pathological diagnosis of clear cell sarcoma of the kidney (CCSK) is challenging as it resembles blastemal Wilms tumor (WT) and other pediatric sarcomas, and does not have any distinctive immunophenotype.. The YWHAEFAM22 translocation t(10;17)(q22;p13) has been reported in a subset of CCSK.. This translocation also occurs in high-grade endometrial sarcoma, in which it is associated with cyclin D1 overexpression.

    Article Title: Characterization of molecular signatures of supratentorial ependymomas.
    Article Snippet: The primary antibodies used were cyclin D1 (1:250 dilution, clone SP4, Thermo Fisher Scientific, Waltham, MA), p65 (1:5000 dilution, clone D14E12, Cell Signaling, Danvers, MA), and L1CAM (1:2000 dilution, clone UJ127.11, Sigma, St. Louis, MO).

    Article Title: Significance of COX-2 and VEGF expression in histopathologic grading and invasiveness of meningiomas.
    Article Snippet: Meningiomas are slow-growing neoplasms that recur locally.. Their morphologic grading does not always correlate with patient outcome.. We evaluated the status of several immunohistochemical markers with histopathologic parameters in various grades of meningioma.Eighty-eight meningioma specimens were examined immunohistochemically to determine the status of Ki-67, cyclin D1, epidermal growth factor receptor (EGFR), cyclooxygenase-2 (COX-2), vascular endothelial growth factor (VEGF), and bcl-2.

    Article Title: CK1α ablation in keratinocytes induces p53-dependent, sunburn-protective skin hyperpigmentation
    Article Snippet: After blocking, sections were incubated overnight at 4 °C with antibodies to the following markers at a proper dilution: CK1α (C-19, 1/1,000; Santa Cruz), γ-H2AX (JBW301, 1/3,000; Millipore), p53 (CM5, 1/200; Leica Biosystems), p21 (F-5, 1/100; Santa Cruz), β-catenin (14 β-catenin, 1/100; BD Bioscience), cyclin D1 (SP4, 1/200; Thermo Fisher Scientific), cleaved caspase 3 (Asp175, 1/200; Cell Signaling Technology), and TRP1 (ab3312, 1/200; Abcam).

    Control:

    Article Title: A Genetic Progression Model of Braf V600E -Induced Intestinal Tumorigenesis Reveals Targets for Therapeutic Intervention
    Article Snippet: For immunohistochemistry formalin-fixed paraffin-embedded tissue sections were dewaxed and placed in a microwave (10 min., 600 watt) to recover antigens before incubation with the following primary antibodies: p53 (NCL-p53-CM5p, Leica Micosystems, Wetzlar, Germany), p21 (C-19) (sc-397; Santa Cruz Biotechnology, Heidelberg, Germany), -catenin (#610154, BD Biosciences, San Diego, CA), phospho- p44/42 MAPK (Erk1/2 Thr202/Tyr204) (D13.14.4E XP, Cell Signaling), Ki-67 (SP6, DCS Hamburg, Germany), c-Myc (N-262) (sc-764, Santa Cruz), cyclin D1 (SP4, Thermo Scientific, Waltham, MA) and cytokeratin 20 (GP-K20, Progen, Heidelberg, Germany).

    Article Title: Plasmacytic ALK-positive large B-cell lymphoma: a potential mimic of extramedullary plasmacytoma.
    Article Snippet: To the Editor: ALK-positive large B-cell lymphoma (ALK+ LBCL) is defined as a B-cell neoplasm that expresses the ALK protein.. This lymphoma occurs in all age groups with a male predominance (M:F ratio, 3:1).. Although the tumor mainly involves lymph nodes, the involvement of various extranodal sites including the gastrointestinal (GI) tract, ovaries, nasopharynx, tongue, brain, liver, bone and spleen has been reported.

    Article Title: Novel Karyotypes and Cyclin D1 Immunoreactivity in Clear Cell Sarcoma of the Kidney
    Article Snippet: Pathological diagnosis of clear cell sarcoma of the kidney (CCSK) is challenging as it resembles blastemal Wilms tumor (WT) and other pediatric sarcomas, and does not have any distinctive immunophenotype.. The YWHAEFAM22 translocation t(10;17)(q22;p13) has been reported in a subset of CCSK.. This translocation also occurs in high-grade endometrial sarcoma, in which it is associated with cyclin D1 overexpression.

    Article Title: Characterization of molecular signatures of supratentorial ependymomas.
    Article Snippet: The primary antibodies used were cyclin D1 (1:250 dilution, clone SP4, Thermo Fisher Scientific, Waltham, MA), p65 (1:5000 dilution, clone D14E12, Cell Signaling, Danvers, MA), and L1CAM (1:2000 dilution, clone UJ127.11, Sigma, St. Louis, MO).

    Article Title: Significance of COX-2 and VEGF expression in histopathologic grading and invasiveness of meningiomas.
    Article Snippet: Meningiomas are slow-growing neoplasms that recur locally.. Their morphologic grading does not always correlate with patient outcome.. We evaluated the status of several immunohistochemical markers with histopathologic parameters in various grades of meningioma.Eighty-eight meningioma specimens were examined immunohistochemically to determine the status of Ki-67, cyclin D1, epidermal growth factor receptor (EGFR), cyclooxygenase-2 (COX-2), vascular endothelial growth factor (VEGF), and bcl-2.

    Article Title: CK1α ablation in keratinocytes induces p53-dependent, sunburn-protective skin hyperpigmentation
    Article Snippet: After blocking, sections were incubated overnight at 4 °C with antibodies to the following markers at a proper dilution: CK1α (C-19, 1/1,000; Santa Cruz), γ-H2AX (JBW301, 1/3,000; Millipore), p53 (CM5, 1/200; Leica Biosystems), p21 (F-5, 1/100; Santa Cruz), β-catenin (14 β-catenin, 1/100; BD Bioscience), cyclin D1 (SP4, 1/200; Thermo Fisher Scientific), cleaved caspase 3 (Asp175, 1/200; Cell Signaling Technology), and TRP1 (ab3312, 1/200; Abcam).

    Reverse Transcription Polymerase Chain Reaction:

    Article Title: A Genetic Progression Model of Braf V600E -Induced Intestinal Tumorigenesis Reveals Targets for Therapeutic Intervention
    Article Snippet: For immunohistochemistry formalin-fixed paraffin-embedded tissue sections were dewaxed and placed in a microwave (10 min., 600 watt) to recover antigens before incubation with the following primary antibodies: p53 (NCL-p53-CM5p, Leica Micosystems, Wetzlar, Germany), p21 (C-19) (sc-397; Santa Cruz Biotechnology, Heidelberg, Germany), -catenin (#610154, BD Biosciences, San Diego, CA), phospho- p44/42 MAPK (Erk1/2 Thr202/Tyr204) (D13.14.4E XP, Cell Signaling), Ki-67 (SP6, DCS Hamburg, Germany), c-Myc (N-262) (sc-764, Santa Cruz), cyclin D1 (SP4, Thermo Scientific, Waltham, MA) and cytokeratin 20 (GP-K20, Progen, Heidelberg, Germany).

    Article Title: Plasmacytic ALK-positive large B-cell lymphoma: a potential mimic of extramedullary plasmacytoma.
    Article Snippet: To the Editor: ALK-positive large B-cell lymphoma (ALK+ LBCL) is defined as a B-cell neoplasm that expresses the ALK protein.. This lymphoma occurs in all age groups with a male predominance (M:F ratio, 3:1).. Although the tumor mainly involves lymph nodes, the involvement of various extranodal sites including the gastrointestinal (GI) tract, ovaries, nasopharynx, tongue, brain, liver, bone and spleen has been reported.

    Article Title: Novel Karyotypes and Cyclin D1 Immunoreactivity in Clear Cell Sarcoma of the Kidney
    Article Snippet: Pathological diagnosis of clear cell sarcoma of the kidney (CCSK) is challenging as it resembles blastemal Wilms tumor (WT) and other pediatric sarcomas, and does not have any distinctive immunophenotype.. The YWHAEFAM22 translocation t(10;17)(q22;p13) has been reported in a subset of CCSK.. This translocation also occurs in high-grade endometrial sarcoma, in which it is associated with cyclin D1 overexpression.

    Article Title: Characterization of molecular signatures of supratentorial ependymomas.
    Article Snippet: The primary antibodies used were cyclin D1 (1:250 dilution, clone SP4, Thermo Fisher Scientific, Waltham, MA), p65 (1:5000 dilution, clone D14E12, Cell Signaling, Danvers, MA), and L1CAM (1:2000 dilution, clone UJ127.11, Sigma, St. Louis, MO).

    Article Title: Significance of COX-2 and VEGF expression in histopathologic grading and invasiveness of meningiomas.
    Article Snippet: Meningiomas are slow-growing neoplasms that recur locally.. Their morphologic grading does not always correlate with patient outcome.. We evaluated the status of several immunohistochemical markers with histopathologic parameters in various grades of meningioma.Eighty-eight meningioma specimens were examined immunohistochemically to determine the status of Ki-67, cyclin D1, epidermal growth factor receptor (EGFR), cyclooxygenase-2 (COX-2), vascular endothelial growth factor (VEGF), and bcl-2.

    Article Title: CK1α ablation in keratinocytes induces p53-dependent, sunburn-protective skin hyperpigmentation
    Article Snippet: After blocking, sections were incubated overnight at 4 °C with antibodies to the following markers at a proper dilution: CK1α (C-19, 1/1,000; Santa Cruz), γ-H2AX (JBW301, 1/3,000; Millipore), p53 (CM5, 1/200; Leica Biosystems), p21 (F-5, 1/100; Santa Cruz), β-catenin (14 β-catenin, 1/100; BD Bioscience), cyclin D1 (SP4, 1/200; Thermo Fisher Scientific), cleaved caspase 3 (Asp175, 1/200; Cell Signaling Technology), and TRP1 (ab3312, 1/200; Abcam).

    Expressing:

    Article Title: A Genetic Progression Model of Braf V600E -Induced Intestinal Tumorigenesis Reveals Targets for Therapeutic Intervention
    Article Snippet: For immunohistochemistry formalin-fixed paraffin-embedded tissue sections were dewaxed and placed in a microwave (10 min., 600 watt) to recover antigens before incubation with the following primary antibodies: p53 (NCL-p53-CM5p, Leica Micosystems, Wetzlar, Germany), p21 (C-19) (sc-397; Santa Cruz Biotechnology, Heidelberg, Germany), -catenin (#610154, BD Biosciences, San Diego, CA), phospho- p44/42 MAPK (Erk1/2 Thr202/Tyr204) (D13.14.4E XP, Cell Signaling), Ki-67 (SP6, DCS Hamburg, Germany), c-Myc (N-262) (sc-764, Santa Cruz), cyclin D1 (SP4, Thermo Scientific, Waltham, MA) and cytokeratin 20 (GP-K20, Progen, Heidelberg, Germany).

    Article Title: Plasmacytic ALK-positive large B-cell lymphoma: a potential mimic of extramedullary plasmacytoma.
    Article Snippet: To the Editor: ALK-positive large B-cell lymphoma (ALK+ LBCL) is defined as a B-cell neoplasm that expresses the ALK protein.. This lymphoma occurs in all age groups with a male predominance (M:F ratio, 3:1).. Although the tumor mainly involves lymph nodes, the involvement of various extranodal sites including the gastrointestinal (GI) tract, ovaries, nasopharynx, tongue, brain, liver, bone and spleen has been reported.

    Article Title: Novel Karyotypes and Cyclin D1 Immunoreactivity in Clear Cell Sarcoma of the Kidney
    Article Snippet: Pathological diagnosis of clear cell sarcoma of the kidney (CCSK) is challenging as it resembles blastemal Wilms tumor (WT) and other pediatric sarcomas, and does not have any distinctive immunophenotype.. The YWHAEFAM22 translocation t(10;17)(q22;p13) has been reported in a subset of CCSK.. This translocation also occurs in high-grade endometrial sarcoma, in which it is associated with cyclin D1 overexpression.

    Article Title: Characterization of molecular signatures of supratentorial ependymomas.
    Article Snippet: The primary antibodies used were cyclin D1 (1:250 dilution, clone SP4, Thermo Fisher Scientific, Waltham, MA), p65 (1:5000 dilution, clone D14E12, Cell Signaling, Danvers, MA), and L1CAM (1:2000 dilution, clone UJ127.11, Sigma, St. Louis, MO).

    Article Title: Significance of COX-2 and VEGF expression in histopathologic grading and invasiveness of meningiomas.
    Article Snippet: Meningiomas are slow-growing neoplasms that recur locally.. Their morphologic grading does not always correlate with patient outcome.. We evaluated the status of several immunohistochemical markers with histopathologic parameters in various grades of meningioma.Eighty-eight meningioma specimens were examined immunohistochemically to determine the status of Ki-67, cyclin D1, epidermal growth factor receptor (EGFR), cyclooxygenase-2 (COX-2), vascular endothelial growth factor (VEGF), and bcl-2.

    Article Title: CK1α ablation in keratinocytes induces p53-dependent, sunburn-protective skin hyperpigmentation
    Article Snippet: After blocking, sections were incubated overnight at 4 °C with antibodies to the following markers at a proper dilution: CK1α (C-19, 1/1,000; Santa Cruz), γ-H2AX (JBW301, 1/3,000; Millipore), p53 (CM5, 1/200; Leica Biosystems), p21 (F-5, 1/100; Santa Cruz), β-catenin (14 β-catenin, 1/100; BD Bioscience), cyclin D1 (SP4, 1/200; Thermo Fisher Scientific), cleaved caspase 3 (Asp175, 1/200; Cell Signaling Technology), and TRP1 (ab3312, 1/200; Abcam).

    Western Blot:

    Article Title: A Genetic Progression Model of Braf V600E -Induced Intestinal Tumorigenesis Reveals Targets for Therapeutic Intervention
    Article Snippet: For immunohistochemistry formalin-fixed paraffin-embedded tissue sections were dewaxed and placed in a microwave (10 min., 600 watt) to recover antigens before incubation with the following primary antibodies: p53 (NCL-p53-CM5p, Leica Micosystems, Wetzlar, Germany), p21 (C-19) (sc-397; Santa Cruz Biotechnology, Heidelberg, Germany), -catenin (#610154, BD Biosciences, San Diego, CA), phospho- p44/42 MAPK (Erk1/2 Thr202/Tyr204) (D13.14.4E XP, Cell Signaling), Ki-67 (SP6, DCS Hamburg, Germany), c-Myc (N-262) (sc-764, Santa Cruz), cyclin D1 (SP4, Thermo Scientific, Waltham, MA) and cytokeratin 20 (GP-K20, Progen, Heidelberg, Germany).

    Article Title: Plasmacytic ALK-positive large B-cell lymphoma: a potential mimic of extramedullary plasmacytoma.
    Article Snippet: To the Editor: ALK-positive large B-cell lymphoma (ALK+ LBCL) is defined as a B-cell neoplasm that expresses the ALK protein.. This lymphoma occurs in all age groups with a male predominance (M:F ratio, 3:1).. Although the tumor mainly involves lymph nodes, the involvement of various extranodal sites including the gastrointestinal (GI) tract, ovaries, nasopharynx, tongue, brain, liver, bone and spleen has been reported.

    Article Title: Novel Karyotypes and Cyclin D1 Immunoreactivity in Clear Cell Sarcoma of the Kidney
    Article Snippet: Pathological diagnosis of clear cell sarcoma of the kidney (CCSK) is challenging as it resembles blastemal Wilms tumor (WT) and other pediatric sarcomas, and does not have any distinctive immunophenotype.. The YWHAEFAM22 translocation t(10;17)(q22;p13) has been reported in a subset of CCSK.. This translocation also occurs in high-grade endometrial sarcoma, in which it is associated with cyclin D1 overexpression.

    Article Title: Characterization of molecular signatures of supratentorial ependymomas.
    Article Snippet: The primary antibodies used were cyclin D1 (1:250 dilution, clone SP4, Thermo Fisher Scientific, Waltham, MA), p65 (1:5000 dilution, clone D14E12, Cell Signaling, Danvers, MA), and L1CAM (1:2000 dilution, clone UJ127.11, Sigma, St. Louis, MO).

    Article Title: Significance of COX-2 and VEGF expression in histopathologic grading and invasiveness of meningiomas.
    Article Snippet: Meningiomas are slow-growing neoplasms that recur locally.. Their morphologic grading does not always correlate with patient outcome.. We evaluated the status of several immunohistochemical markers with histopathologic parameters in various grades of meningioma.Eighty-eight meningioma specimens were examined immunohistochemically to determine the status of Ki-67, cyclin D1, epidermal growth factor receptor (EGFR), cyclooxygenase-2 (COX-2), vascular endothelial growth factor (VEGF), and bcl-2.

    Article Title: CK1α ablation in keratinocytes induces p53-dependent, sunburn-protective skin hyperpigmentation
    Article Snippet: After blocking, sections were incubated overnight at 4 °C with antibodies to the following markers at a proper dilution: CK1α (C-19, 1/1,000; Santa Cruz), γ-H2AX (JBW301, 1/3,000; Millipore), p53 (CM5, 1/200; Leica Biosystems), p21 (F-5, 1/100; Santa Cruz), β-catenin (14 β-catenin, 1/100; BD Bioscience), cyclin D1 (SP4, 1/200; Thermo Fisher Scientific), cleaved caspase 3 (Asp175, 1/200; Cell Signaling Technology), and TRP1 (ab3312, 1/200; Abcam).

    Immunohistochemistry:

    Article Title: A Genetic Progression Model of Braf V600E -Induced Intestinal Tumorigenesis Reveals Targets for Therapeutic Intervention
    Article Snippet: For immunohistochemistry formalin-fixed paraffin-embedded tissue sections were dewaxed and placed in a microwave (10 min., 600 watt) to recover antigens before incubation with the following primary antibodies: p53 (NCL-p53-CM5p, Leica Micosystems, Wetzlar, Germany), p21 (C-19) (sc-397; Santa Cruz Biotechnology, Heidelberg, Germany), -catenin (#610154, BD Biosciences, San Diego, CA), phospho- p44/42 MAPK (Erk1/2 Thr202/Tyr204) (D13.14.4E XP, Cell Signaling), Ki-67 (SP6, DCS Hamburg, Germany), c-Myc (N-262) (sc-764, Santa Cruz), cyclin D1 (SP4, Thermo Scientific, Waltham, MA) and cytokeratin 20 (GP-K20, Progen, Heidelberg, Germany).

    Article Title: Plasmacytic ALK-positive large B-cell lymphoma: a potential mimic of extramedullary plasmacytoma.
    Article Snippet: To the Editor: ALK-positive large B-cell lymphoma (ALK+ LBCL) is defined as a B-cell neoplasm that expresses the ALK protein.. This lymphoma occurs in all age groups with a male predominance (M:F ratio, 3:1).. Although the tumor mainly involves lymph nodes, the involvement of various extranodal sites including the gastrointestinal (GI) tract, ovaries, nasopharynx, tongue, brain, liver, bone and spleen has been reported.

    Article Title: Novel Karyotypes and Cyclin D1 Immunoreactivity in Clear Cell Sarcoma of the Kidney
    Article Snippet: Pathological diagnosis of clear cell sarcoma of the kidney (CCSK) is challenging as it resembles blastemal Wilms tumor (WT) and other pediatric sarcomas, and does not have any distinctive immunophenotype.. The YWHAEFAM22 translocation t(10;17)(q22;p13) has been reported in a subset of CCSK.. This translocation also occurs in high-grade endometrial sarcoma, in which it is associated with cyclin D1 overexpression.

    Article Title: Characterization of molecular signatures of supratentorial ependymomas.
    Article Snippet: The primary antibodies used were cyclin D1 (1:250 dilution, clone SP4, Thermo Fisher Scientific, Waltham, MA), p65 (1:5000 dilution, clone D14E12, Cell Signaling, Danvers, MA), and L1CAM (1:2000 dilution, clone UJ127.11, Sigma, St. Louis, MO).

    Article Title: Significance of COX-2 and VEGF expression in histopathologic grading and invasiveness of meningiomas.
    Article Snippet: Meningiomas are slow-growing neoplasms that recur locally.. Their morphologic grading does not always correlate with patient outcome.. We evaluated the status of several immunohistochemical markers with histopathologic parameters in various grades of meningioma.Eighty-eight meningioma specimens were examined immunohistochemically to determine the status of Ki-67, cyclin D1, epidermal growth factor receptor (EGFR), cyclooxygenase-2 (COX-2), vascular endothelial growth factor (VEGF), and bcl-2.

    Article Title: CK1α ablation in keratinocytes induces p53-dependent, sunburn-protective skin hyperpigmentation
    Article Snippet: After blocking, sections were incubated overnight at 4 °C with antibodies to the following markers at a proper dilution: CK1α (C-19, 1/1,000; Santa Cruz), γ-H2AX (JBW301, 1/3,000; Millipore), p53 (CM5, 1/200; Leica Biosystems), p21 (F-5, 1/100; Santa Cruz), β-catenin (14 β-catenin, 1/100; BD Bioscience), cyclin D1 (SP4, 1/200; Thermo Fisher Scientific), cleaved caspase 3 (Asp175, 1/200; Cell Signaling Technology), and TRP1 (ab3312, 1/200; Abcam).

    Staining:

    Article Title: A Genetic Progression Model of Braf V600E -Induced Intestinal Tumorigenesis Reveals Targets for Therapeutic Intervention
    Article Snippet: For immunohistochemistry formalin-fixed paraffin-embedded tissue sections were dewaxed and placed in a microwave (10 min., 600 watt) to recover antigens before incubation with the following primary antibodies: p53 (NCL-p53-CM5p, Leica Micosystems, Wetzlar, Germany), p21 (C-19) (sc-397; Santa Cruz Biotechnology, Heidelberg, Germany), -catenin (#610154, BD Biosciences, San Diego, CA), phospho- p44/42 MAPK (Erk1/2 Thr202/Tyr204) (D13.14.4E XP, Cell Signaling), Ki-67 (SP6, DCS Hamburg, Germany), c-Myc (N-262) (sc-764, Santa Cruz), cyclin D1 (SP4, Thermo Scientific, Waltham, MA) and cytokeratin 20 (GP-K20, Progen, Heidelberg, Germany).

    Article Title: Plasmacytic ALK-positive large B-cell lymphoma: a potential mimic of extramedullary plasmacytoma.
    Article Snippet: To the Editor: ALK-positive large B-cell lymphoma (ALK+ LBCL) is defined as a B-cell neoplasm that expresses the ALK protein.. This lymphoma occurs in all age groups with a male predominance (M:F ratio, 3:1).. Although the tumor mainly involves lymph nodes, the involvement of various extranodal sites including the gastrointestinal (GI) tract, ovaries, nasopharynx, tongue, brain, liver, bone and spleen has been reported.

    Article Title: Novel Karyotypes and Cyclin D1 Immunoreactivity in Clear Cell Sarcoma of the Kidney
    Article Snippet: Pathological diagnosis of clear cell sarcoma of the kidney (CCSK) is challenging as it resembles blastemal Wilms tumor (WT) and other pediatric sarcomas, and does not have any distinctive immunophenotype.. The YWHAEFAM22 translocation t(10;17)(q22;p13) has been reported in a subset of CCSK.. This translocation also occurs in high-grade endometrial sarcoma, in which it is associated with cyclin D1 overexpression.

    Article Title: Characterization of molecular signatures of supratentorial ependymomas.
    Article Snippet: The primary antibodies used were cyclin D1 (1:250 dilution, clone SP4, Thermo Fisher Scientific, Waltham, MA), p65 (1:5000 dilution, clone D14E12, Cell Signaling, Danvers, MA), and L1CAM (1:2000 dilution, clone UJ127.11, Sigma, St. Louis, MO).

    Article Title: Significance of COX-2 and VEGF expression in histopathologic grading and invasiveness of meningiomas.
    Article Snippet: Meningiomas are slow-growing neoplasms that recur locally.. Their morphologic grading does not always correlate with patient outcome.. We evaluated the status of several immunohistochemical markers with histopathologic parameters in various grades of meningioma.Eighty-eight meningioma specimens were examined immunohistochemically to determine the status of Ki-67, cyclin D1, epidermal growth factor receptor (EGFR), cyclooxygenase-2 (COX-2), vascular endothelial growth factor (VEGF), and bcl-2.

    Article Title: CK1α ablation in keratinocytes induces p53-dependent, sunburn-protective skin hyperpigmentation
    Article Snippet: After blocking, sections were incubated overnight at 4 °C with antibodies to the following markers at a proper dilution: CK1α (C-19, 1/1,000; Santa Cruz), γ-H2AX (JBW301, 1/3,000; Millipore), p53 (CM5, 1/200; Leica Biosystems), p21 (F-5, 1/100; Santa Cruz), β-catenin (14 β-catenin, 1/100; BD Bioscience), cyclin D1 (SP4, 1/200; Thermo Fisher Scientific), cleaved caspase 3 (Asp175, 1/200; Cell Signaling Technology), and TRP1 (ab3312, 1/200; Abcam).

    Immunohistochemical staining:

    Article Title: A Genetic Progression Model of Braf V600E -Induced Intestinal Tumorigenesis Reveals Targets for Therapeutic Intervention
    Article Snippet: For immunohistochemistry formalin-fixed paraffin-embedded tissue sections were dewaxed and placed in a microwave (10 min., 600 watt) to recover antigens before incubation with the following primary antibodies: p53 (NCL-p53-CM5p, Leica Micosystems, Wetzlar, Germany), p21 (C-19) (sc-397; Santa Cruz Biotechnology, Heidelberg, Germany), -catenin (#610154, BD Biosciences, San Diego, CA), phospho- p44/42 MAPK (Erk1/2 Thr202/Tyr204) (D13.14.4E XP, Cell Signaling), Ki-67 (SP6, DCS Hamburg, Germany), c-Myc (N-262) (sc-764, Santa Cruz), cyclin D1 (SP4, Thermo Scientific, Waltham, MA) and cytokeratin 20 (GP-K20, Progen, Heidelberg, Germany).

    Article Title: Plasmacytic ALK-positive large B-cell lymphoma: a potential mimic of extramedullary plasmacytoma.
    Article Snippet: To the Editor: ALK-positive large B-cell lymphoma (ALK+ LBCL) is defined as a B-cell neoplasm that expresses the ALK protein.. This lymphoma occurs in all age groups with a male predominance (M:F ratio, 3:1).. Although the tumor mainly involves lymph nodes, the involvement of various extranodal sites including the gastrointestinal (GI) tract, ovaries, nasopharynx, tongue, brain, liver, bone and spleen has been reported.

    Article Title: Novel Karyotypes and Cyclin D1 Immunoreactivity in Clear Cell Sarcoma of the Kidney
    Article Snippet: Pathological diagnosis of clear cell sarcoma of the kidney (CCSK) is challenging as it resembles blastemal Wilms tumor (WT) and other pediatric sarcomas, and does not have any distinctive immunophenotype.. The YWHAEFAM22 translocation t(10;17)(q22;p13) has been reported in a subset of CCSK.. This translocation also occurs in high-grade endometrial sarcoma, in which it is associated with cyclin D1 overexpression.

    Article Title: Characterization of molecular signatures of supratentorial ependymomas.
    Article Snippet: The primary antibodies used were cyclin D1 (1:250 dilution, clone SP4, Thermo Fisher Scientific, Waltham, MA), p65 (1:5000 dilution, clone D14E12, Cell Signaling, Danvers, MA), and L1CAM (1:2000 dilution, clone UJ127.11, Sigma, St. Louis, MO).

    Article Title: Significance of COX-2 and VEGF expression in histopathologic grading and invasiveness of meningiomas.
    Article Snippet: Meningiomas are slow-growing neoplasms that recur locally.. Their morphologic grading does not always correlate with patient outcome.. We evaluated the status of several immunohistochemical markers with histopathologic parameters in various grades of meningioma.Eighty-eight meningioma specimens were examined immunohistochemically to determine the status of Ki-67, cyclin D1, epidermal growth factor receptor (EGFR), cyclooxygenase-2 (COX-2), vascular endothelial growth factor (VEGF), and bcl-2.

    Article Title: CK1α ablation in keratinocytes induces p53-dependent, sunburn-protective skin hyperpigmentation
    Article Snippet: After blocking, sections were incubated overnight at 4 °C with antibodies to the following markers at a proper dilution: CK1α (C-19, 1/1,000; Santa Cruz), γ-H2AX (JBW301, 1/3,000; Millipore), p53 (CM5, 1/200; Leica Biosystems), p21 (F-5, 1/100; Santa Cruz), β-catenin (14 β-catenin, 1/100; BD Bioscience), cyclin D1 (SP4, 1/200; Thermo Fisher Scientific), cleaved caspase 3 (Asp175, 1/200; Cell Signaling Technology), and TRP1 (ab3312, 1/200; Abcam).

    Formalin-fixed Paraffin-Embedded:

    Article Title: A Genetic Progression Model of Braf V600E -Induced Intestinal Tumorigenesis Reveals Targets for Therapeutic Intervention
    Article Snippet: For immunohistochemistry formalin-fixed paraffin-embedded tissue sections were dewaxed and placed in a microwave (10 min., 600 watt) to recover antigens before incubation with the following primary antibodies: p53 (NCL-p53-CM5p, Leica Micosystems, Wetzlar, Germany), p21 (C-19) (sc-397; Santa Cruz Biotechnology, Heidelberg, Germany), -catenin (#610154, BD Biosciences, San Diego, CA), phospho- p44/42 MAPK (Erk1/2 Thr202/Tyr204) (D13.14.4E XP, Cell Signaling), Ki-67 (SP6, DCS Hamburg, Germany), c-Myc (N-262) (sc-764, Santa Cruz), cyclin D1 (SP4, Thermo Scientific, Waltham, MA) and cytokeratin 20 (GP-K20, Progen, Heidelberg, Germany).

    Article Title: Plasmacytic ALK-positive large B-cell lymphoma: a potential mimic of extramedullary plasmacytoma.
    Article Snippet: To the Editor: ALK-positive large B-cell lymphoma (ALK+ LBCL) is defined as a B-cell neoplasm that expresses the ALK protein.. This lymphoma occurs in all age groups with a male predominance (M:F ratio, 3:1).. Although the tumor mainly involves lymph nodes, the involvement of various extranodal sites including the gastrointestinal (GI) tract, ovaries, nasopharynx, tongue, brain, liver, bone and spleen has been reported.

    Article Title: Novel Karyotypes and Cyclin D1 Immunoreactivity in Clear Cell Sarcoma of the Kidney
    Article Snippet: Pathological diagnosis of clear cell sarcoma of the kidney (CCSK) is challenging as it resembles blastemal Wilms tumor (WT) and other pediatric sarcomas, and does not have any distinctive immunophenotype.. The YWHAEFAM22 translocation t(10;17)(q22;p13) has been reported in a subset of CCSK.. This translocation also occurs in high-grade endometrial sarcoma, in which it is associated with cyclin D1 overexpression.

    Article Title: Characterization of molecular signatures of supratentorial ependymomas.
    Article Snippet: The primary antibodies used were cyclin D1 (1:250 dilution, clone SP4, Thermo Fisher Scientific, Waltham, MA), p65 (1:5000 dilution, clone D14E12, Cell Signaling, Danvers, MA), and L1CAM (1:2000 dilution, clone UJ127.11, Sigma, St. Louis, MO).

    Article Title: Significance of COX-2 and VEGF expression in histopathologic grading and invasiveness of meningiomas.
    Article Snippet: Meningiomas are slow-growing neoplasms that recur locally.. Their morphologic grading does not always correlate with patient outcome.. We evaluated the status of several immunohistochemical markers with histopathologic parameters in various grades of meningioma.Eighty-eight meningioma specimens were examined immunohistochemically to determine the status of Ki-67, cyclin D1, epidermal growth factor receptor (EGFR), cyclooxygenase-2 (COX-2), vascular endothelial growth factor (VEGF), and bcl-2.

    Article Title: CK1α ablation in keratinocytes induces p53-dependent, sunburn-protective skin hyperpigmentation
    Article Snippet: After blocking, sections were incubated overnight at 4 °C with antibodies to the following markers at a proper dilution: CK1α (C-19, 1/1,000; Santa Cruz), γ-H2AX (JBW301, 1/3,000; Millipore), p53 (CM5, 1/200; Leica Biosystems), p21 (F-5, 1/100; Santa Cruz), β-catenin (14 β-catenin, 1/100; BD Bioscience), cyclin D1 (SP4, 1/200; Thermo Fisher Scientific), cleaved caspase 3 (Asp175, 1/200; Cell Signaling Technology), and TRP1 (ab3312, 1/200; Abcam).



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    Image Search Results


    Association between  cyclin   D1  expression and clinicopathological factors in SIAC.

    Journal: Cancers

    Article Title: Prognostic Significance of Cyclin D1 Expression in Small Intestinal Adenocarcinoma

    doi: 10.3390/cancers15205032

    Figure Lengend Snippet: Association between cyclin D1 expression and clinicopathological factors in SIAC.

    Article Snippet: The TMA sections were immunostained using an anti-cyclin D1 antibody (clone SP4; Cell Marque, Darmstadt, Germany) and the Ventana BenchMark XT immunostainer (Ventana Medical System, Tucson, AZ, USA).

    Techniques: Expressing

    Cyclin D1 expression in normal mucosa of the small intestine. The cyclin D1 was expressed in the transitional zone of the crypt at the lower portion of the gland of normal small intestinal mucosa (original magnification ×200).

    Journal: Cancers

    Article Title: Prognostic Significance of Cyclin D1 Expression in Small Intestinal Adenocarcinoma

    doi: 10.3390/cancers15205032

    Figure Lengend Snippet: Cyclin D1 expression in normal mucosa of the small intestine. The cyclin D1 was expressed in the transitional zone of the crypt at the lower portion of the gland of normal small intestinal mucosa (original magnification ×200).

    Article Snippet: The TMA sections were immunostained using an anti-cyclin D1 antibody (clone SP4; Cell Marque, Darmstadt, Germany) and the Ventana BenchMark XT immunostainer (Ventana Medical System, Tucson, AZ, USA).

    Techniques: Expressing

    Representative images of cyclin D1 expression in SIAC. Cyclin D1 Low showed ( A ) a score of 0, ( B ) a score of 1, and ( C ) a score of 2. Cyclin D1 High had ( D ) a score of 14, ( E ) a score of 18, and ( F ) a score of 30 (original magnification ×100).

    Journal: Cancers

    Article Title: Prognostic Significance of Cyclin D1 Expression in Small Intestinal Adenocarcinoma

    doi: 10.3390/cancers15205032

    Figure Lengend Snippet: Representative images of cyclin D1 expression in SIAC. Cyclin D1 Low showed ( A ) a score of 0, ( B ) a score of 1, and ( C ) a score of 2. Cyclin D1 High had ( D ) a score of 14, ( E ) a score of 18, and ( F ) a score of 30 (original magnification ×100).

    Article Snippet: The TMA sections were immunostained using an anti-cyclin D1 antibody (clone SP4; Cell Marque, Darmstadt, Germany) and the Ventana BenchMark XT immunostainer (Ventana Medical System, Tucson, AZ, USA).

    Techniques: Expressing

    Association between clinicopathological factors and OS in SIAC.

    Journal: Cancers

    Article Title: Prognostic Significance of Cyclin D1 Expression in Small Intestinal Adenocarcinoma

    doi: 10.3390/cancers15205032

    Figure Lengend Snippet: Association between clinicopathological factors and OS in SIAC.

    Article Snippet: The TMA sections were immunostained using an anti-cyclin D1 antibody (clone SP4; Cell Marque, Darmstadt, Germany) and the Ventana BenchMark XT immunostainer (Ventana Medical System, Tucson, AZ, USA).

    Techniques: Expressing

    Univariate survival analysis of cyclin D1 High in SIAC patients. The patients with cyclin D1 High had significantly longer survival times than those with cyclin D1 Low ( p = 0.005).

    Journal: Cancers

    Article Title: Prognostic Significance of Cyclin D1 Expression in Small Intestinal Adenocarcinoma

    doi: 10.3390/cancers15205032

    Figure Lengend Snippet: Univariate survival analysis of cyclin D1 High in SIAC patients. The patients with cyclin D1 High had significantly longer survival times than those with cyclin D1 Low ( p = 0.005).

    Article Snippet: The TMA sections were immunostained using an anti-cyclin D1 antibody (clone SP4; Cell Marque, Darmstadt, Germany) and the Ventana BenchMark XT immunostainer (Ventana Medical System, Tucson, AZ, USA).

    Techniques:

    Prognostic impact of cyclin D1 expression in SIAC depending on tumor stage. ( A ) Cyclin D1 High significantly predicted the longer OS of patients in the lower stage group (stages I and II, n = 105; p < 0.001), while ( B ) no significant difference in survival was identified between the cyclin D1 High and cyclin D1 Low groups in the higher stage group (stage III, n = 106; p = 0.629).

    Journal: Cancers

    Article Title: Prognostic Significance of Cyclin D1 Expression in Small Intestinal Adenocarcinoma

    doi: 10.3390/cancers15205032

    Figure Lengend Snippet: Prognostic impact of cyclin D1 expression in SIAC depending on tumor stage. ( A ) Cyclin D1 High significantly predicted the longer OS of patients in the lower stage group (stages I and II, n = 105; p < 0.001), while ( B ) no significant difference in survival was identified between the cyclin D1 High and cyclin D1 Low groups in the higher stage group (stage III, n = 106; p = 0.629).

    Article Snippet: The TMA sections were immunostained using an anti-cyclin D1 antibody (clone SP4; Cell Marque, Darmstadt, Germany) and the Ventana BenchMark XT immunostainer (Ventana Medical System, Tucson, AZ, USA).

    Techniques: Expressing